PROFESORADO UNIVERSIDAD COMPLUTENSE DE MADRID
Born in Madrid, Luis got his Bachelor degree in Chemistry in 1991 (UCM) and his PhD in 1995 (Cum laude and UCM Thesis award). After a postdoct stay in the University of North Carolina at Chapel Hill with prof. M. Brookhart he joined the Universidad San Pablo CEU in Madrid as an assistant professor in 1997 where he worked until 2002. Luis then moved to the pharmaceutical industry for almost four years (Eli Lilly, Spain) and in January 2006 he returned to the university as a Ramon y Cajal Researcher being part of the Bioorganometallic chemistry group.
Research along these years has been centered in multiple areas: Fischer Complexes chemistry, catalysis, Pauson-Khand reaction, metathesis, medicinal chemistry, scale up processes and is actually centered in bioorganometallic chemistry.
Aurelio G. Csákÿ
Aurelio G. Csákÿ received his Ph. D. from Universidad Complutense de Madrid (UCM) under the supervision of Prof. J. Plumet. He has carried out stays at the EHICS (Strasbourg, France) in the group of Prof. A. Solladié and at the EPFL (Lausanne, Switzerland) in the group of Prof. P. Vogel before starting his independent carrier. He is currently Full Professor of Organic Chemistry at UCM and Head of the Instituto Pluridisciplinar UCM. His research interests include stereochemistry, catalysis and the development of new synthetic methods towards pharmaceutically active compounds.
Salvatore Filippone is an associate professor at UCM.
He obtained his Ph.D. at the University of Pavia and he spent two postdoctoral years at ENS of Paris. Since 2002, he has been working at UCM in the group of “Organic Molecular Materials”. His research interests span from the asymmetric synthesis to the organic devices with a particular emphasis for the chemistry of Fullerenes.
David García Fresnadillo
David earned his Ph.D. in Organic Chemistry in 1996, Universidad Complutense de Madrid, UCM, Spain. He performed several research stays with Profs. A. M. Braun and E. Oliveros (Engler-Bunte Institüt, University of Karlsruhe, Germany), working on singlet oxygen photosensitization with Ru(II) complexes. Stay at the Laboratory of Water Analysis in 1997 (Geological and Mining Institute of Spain, Madrid). Research and Teaching Assistant at UCM between 1998 and 2002. Postdoctoral researcher in 1999 with Prof. A. Kirsch-DeMesmaeker (Free University of Brussels, Belgium), where he studied the photophysics and photochemistry of DNA oligonucleotides labelled with luminescent Ru(II) complexes as molecular photoprobes and phototools for DNA. In 2003 he became Assistant Professor at UCM and started to develop singlet oxygen photosensitizing materials for environmental and biomedical applications. In 2009, he was promoted to his present tenured position of Associate Professor of Organic Chemistry in the Department of Organic Chemistry, Faculty of Chemical Sciences, UCM. In 2010 he joined the Organic Molecular Materials research group led by Prof. Nazario Martín (http://www.nazariomartingroup.com/Members.html#David). His current research interests are focused on the synthesis, structural and photophysical characterization of carbon nanostructures with the aim of developing applications in the fields of photochemistry and photobiology.
His areas of expertise include the photophysical and photochemical characterization of excited states in homogeneous and (micro/nano)heterogeneous media, the study of photoinduced energy and electron transfer processes, singlet oxygen photosensitization, photooxidation reactions, photodynamic inactivation of microorganisms, solar reactors for water disinfection and decontamination, phototools, photoprobes, optical sensors, and photochemistry of organic molecular materials and applications thereof.
He is a Member of the Spanish Royal Society of Chemistry (RSEQ), RSEQ’s Group of Photochemistry, the European Photochemistry Association, and the European Society for Photobiology, and has published several papers, reviews and book chapters in the fields of chemical dyes and materials for optical sensors and singlet oxygen photosensitization. He has supervised several awarded research projects for young researchers and several UCM projects on Innovation and Improvement of Teaching Quality between 2005 and 2009 (Vice-Rectorate for Quality Assessment). He is the author of four books and many communications to conferences published in this field.
List of selected recent publications:
Research Articles and Reviews
1) Exploring BODIPY Derivatives as Singlet Oxygen Photosensitizers for PDT. Photochem. Photobiol. 2020. Review. DOI: 10.1111/php.13232.
2) π‑Extended corannulene-based nanographenes: Selective formation of negative curvature. J. Am. Chem. Soc. 2018, 140, 17188-17196. DOI: 10.1021/jacs.8b09992.
3) Singlet oxygen photosensitizing materials for point‐of‐use water disinfection with solar reactors. ChemPhotoChem, 2018, 2, 512-534. Very Important Paper, Review. DOI: 10.1002/cptc.201800062.
4) Rhodanine-based dyes absorbing in the entire visible spectrum. Org. Chem. Front., 2017, 4, 1024-1028. DOI: 10.1039/C6QO00760K.
5) Towards improved halogenated BODIPY photosensitizers: clues on structural designs and heavy atom substitution patterns. Phys. Chem. Chem. Phys., 2017, 19, 69-72. DOI: 10.1039/C6CP06448E.
6) Photochemical oxidation of thioketones by singlet molecular oxygen revisited: Insights into photoproducts, kinetics, and reaction mechanism. J. Org. Chem., 2015, 80, 10575-10584. DOI: 10.1021/acs.joc.5b01710.
7) Phototransformation of model micropollutants in water samples by photocatalytic singlet oxygen production in heterogeneous medium. Appl. Catal. B: Environ., 2014, 160-161, 445-455. DOI: 10.1016/j.apcatb.2014.05.050.
8) Helicobacter pylori inactivation and virulence gene damage using a supported sensitiser for photodynamic therapy. Eur. J. Med. Chem., 2013, 68, 284-290. DOI: 10.1016/j.ejmech.2013.07.023.
1) “Reference photosensitisers for the production of singlet oxygen” in Singlet Oxygen: Applications in Biosciences and Nanosciences. S. Nonell, C. Flors, eds. Comprehensive Series in Photochemical and Photobiological Sciences, G. Jori, M. Trotta, Series eds. Vol. 1, pp. 105-143. Royal Society of Chemistry, Cambridge, 2016. ISBN: 978-1-78262-038-9.
1) Luminescent pigments and their use in security applications. US PATENT US2014/0158019 A1. Fábrica Nacional de Moneda y Timbre - Real Casa de la Moneda.
Rafael Gómez Aspe
Rafael Gómez Aspe is Associate Professor at the Universidad Complutense de Madrid. Previously he was a Ramón y Cajal Researcher and he has worked in the Technische Universiteit Eindhoven (TUE), in industry, and at the Université Libre de Bruxelles (ULB).
Currently, he is part of the research group “Supramolecular Polymers”, where he carries out studies on the design, synthesis and characterization of organic molecules that self-assemble to form supramolecular structures.
He is also interested in opto and electroactive organic molecular and polymeric materials and in the chemistry of natural products.
Antonio Herrera Fernández
Family Name: Herrera Fernández
First Name: Antonio
Title: Ph D
Position: Full Professor of Organic Chemistry
Career: Chemistry; Period: 1969-74; Doctor degree: 1978 (both at Madrid Complutense University, Madrid, Spain)
Postdoc period: 1979-81, Max-Planck-Institut für Kohlenforshung, Mülheim a.d. Ruhr (Germany), fellowship from the Max-Planck-Gesellshaft
Visiting Professor: 1987, Max-Planck-Institut für Kohlenforshung, Mülheim a.d. Ruhr (Germany), fellowship from the DAAD. 2007, Weizmann Institute of Science, Rehovot (Israel), fellowship from the Complutense University
Work address: Department of Organic Chemistry, Faculty of Chemistry; Complutense University, E-28040 Madrid, Spain
Research fields of interest:
Synthesis of heterociclyc systems
Structure elucidation of organic compounds
Applications of the Ultrafast NMR techniques for the monitoring of reactive systems
19 National Research projects (MEC, AECI, MCYT, CAM, INIA); 1 European research projects, 2 research projects (private funds). Director of 8 Ph D.
85 Scientific Publications in international journals of high index impact, 5 scientific books translated, 1 scientic book published, 1 scientific book chapter published.
María Luz López Rodríguez
Full Professor of Organic Chemistry.
She received her B.S. with Honors in Chemistry and her PhD from Universidad Complutense de Madrid (UCM). Afterwards, she carried out a postdoctoral stay in the Memorial Sloan-Kettering Cancer Center and Florida University (USA) with a Fulbright Grant.
1985-2004: Associate Professor in the Department of Organic Chemistry (UCM University).
2004 to present: Full Professor in the Department of Organic Chemistry (UCM University).
Head of the Medicinal Chemistry Group in the Department of Organic Chemistry (UCM University).
-Design and synthesis of ligands of the lysophosphatidic acid (LPA) Rs.
-Development of new agents acting on the endogenous cannabinoid system: CB1, CB2 Rs; monoacylglycerol lipase (MAGL).
-Development of allosteric modulators for type A GPCRs.
-Design and synthesis of new anticancer drugs: isoprenylcysteine carboxylmethyltransferase (ICMT) and fatty acid synthase (FASN) inhibitors.
-Development of FtsZ inhibitors as new antibacterials.
-Development of chemical probes for the study of GPCRs and for the identification of novel therapeutic targets.
Publications: 127 original articles
Patents: 13 international patents (12 PCT and 1 USA)
Editorial Board of Scientific Journals:
Associate Editor of Current Medicinal Chemistry-Central Nervous System Agents.
Regional Editor of Minireviews in Current Medicinal Chemistry.
Editor Advisory Board of Current Medicinal Chemistry.
Advisory Board of MedChemComm.
Roberto Martínez Álvarez
Doctor in Organic Chemistry 1981 (Complutense University, Madrid, Spain), Postdoctoral stay in 1986 in the Institut für Organische Chemie, Universität Tübingen (Germany), fellowship from the DAAD (German Academic Exchange Service) and during the period 1989-1990, Institut für Organische Chemie, Universität Tübingen (Germany), fellowship of the Alexander von Humboldt Foundation.
Visiting Professor in 2000-2003 in the Institut für Organische Chemie, Universität Tübingen (Germany). Currently, Head of the Organic Chemistry Department of the Chemistry Faculty of the Complutense University, Madrid, Spain.
Synthesis of heterocyclic systems; Structure elucidation of organic compounds; Mass Spectrometry of fullerene derivatives; Application of the Ultra-fast NMR technique for the monitoring of organic reaction mechanisms in real time.
14 National Research projects (MEC, AECI, MCYT, CAM, INIA); 2 European research projects, 2 research project (private funds). Director of 5 PhD. 130 Scientific Publications in international journals of high index impact, 5 scientific books translated, 1 scientific book published, 1 scientific book chapter published.
From December 2006 to November 2012, member of the Temporary Working Group on Sample and Analysis depending on the SAB (Scientific Advisory Board) of the OPCW (Organisation for the Prohibition of Chemical Weapons, The Hague, Netherlands).
From December 2011 member of the Scientific Advisory Board (SAB) of the OPCW
From January 2013 chair of the Temporary Working Group on Verification depending on the SAB of the OPCW.
Member of the Editorial Board of the “Open Spectroscopy Journal”
From 2000, Scientific advisor of the Laboratorio Central de la Marañosa (Madrid, Spain), currently designed laboratoty of the OPCW.
Current position Associate Professor
Curriculum & Projects
- Bachelor´s degree in Biochemistry (Complutense University, Madrid, Spain). Graduated with honors
- PhD in the Organic Chemistry Program (Complutense University, Madrid, Spain) with honors
- Postdoctoral research associate at The Scripps Research Institute (La Jolla, California, USA) with a MEC-Fulbright scholarship under the supervision of Prof. Benjamin F. Cravatt
- Ramon y Cajal Research Associate (Organic Chemistry Department, Complutense University, Madrid, Spain).
Areas of interest: medicinal chemistry and chemical biology.
Research lines: endogenous cannabinoid system (monoacylglycerol lipase, cannabinoid receptors), lysophosphatic acid receptors, cancer (fatty acid synthase, isoprenylcysteine carboxyl methyltransferase), development of chemical probes for the study of G protein-coupled receptors.
Awards and Recognitions:
2001: Coy W. Waller Student Merit Award. International Cannabinoid Research Society.
2002: Spanish Society of Research on Cannabinoids Award.
2004: Scientific Achievement Award. International Cannabinoid Research Society.
2011: Runner-up of the European Federation of Medicinal Chemistry Prize for a Young Medicinal Chemistry in Academia.
2012: Sigma-Aldrich Young Investigator Award from Royal Spanish Society of Chemistry.
2013: Best oral communication award. Spanish Society of Medicinal Chemistry.
Positions in Scientific Societies:
- Education and Training Committee of the European Federation of Medicinal Chemistry (from January 2011).
Patents: PCT ES01/00305, WO 02/12167 A1; EP07110956, PCT/EP2008058099 (transferred to Italfarmaco); PCT/ES2014/070071.
For a list of publications, see:
Miguel Ángel Sierra Rodríguez
Born 1960 (Villamiel-Toledo-Spain). Miguel A. Sierra obtained is Bachelor in Organic Chemistry in 1982 with an overall A+ grade, and his Ph. D. in Organic Chemistry (Cum Laude, Honors, UCM Ph.D excellence award) in 1987. He was appointed Profesor Ayudante (Assistant Professor) in 1987 and, after a post-doctoral stay in Colorado State University (1988-1989) in the laboratories of Prof. Louis S. Hegedus, came back to Spain where in 1990 he obtained a permanent position at the UCM as Profesor Titular of Organic Chemistry (Tenured Associated Professor). He was promoted to Catedrático Habilitado de Química Orgánica in 2003 and to Catedrático de Química Orgánica (Full Professor) in 2005. Currently, he is the director of the Bio-Organometallic Chemistry Group of the UCM. He has published 180 scientific articles, four books, and 5 patents, with one products for correcting iron-chlorosis already in the market (Ultraferro®), the second (Tarvox®) in precomercialization and a third compound (DCHA) now in the pilot plant. He has directed 19 PhD Thesis and currently he is the advisor of 7 additional PhD students.
Prof. Sierra consulted the Nuclear, Biological and Chemical (NBQ) laboratory and the Energetic Materials laboratory of the Spanish Ministery of Defense, and has developed joint research projects with both laboratories, as well as with several agrochemical companies. He was a member of the Scientific Advisory Board (SAB) of the Organization for the Prohibition of Chemical Weapons (OPCW) (2003-2009), the Chairman of the TWG on Sampling and Analysis of the OPCW (2004-2007). He was the Secretary of the Organic Group of the Spanish Chemical Society (2005-2012), he has been a member of the board of this Society (2006-2012), and he is an Honorary Member of the Sociedad Química Argentina. He was awarded (2003) the Military Cross with white ribbon, and the Ignacio Ribas Excellence Award from the Organic Division of the Spanish Chemical Society (2013). He is the General Editor of Anales de Química since 2014. Apart from research talks, he is a habitual lecturer in different universities, colleges and research centers in topics related to the chemical weapon destruction, social aspects about the use and misuse of conventional and chemical weapons, their history and the ethical aspects of the interrelation between chemical knowledge and society. He acts as regular referee (> 50 articles year) for the world top journals of general, organic, organometallic and inorganic chemistry, the National Science Foundation of the USA and the Petroleum Research Found administrated by the American Chemical Society, the National Research Foundation (NRF) (Sudafrica), and the Agencia Nacional de Promoción Científica y Tecnológica (ANPCyT) from Argentina, as well as for different Spanish Evaluation Agencies. Member of the Committee for the Accreditation of Profesores Titulares of the Spanish National Agency for the Evaluation of the Quality and Accreditation (ANECA) (2014-)
Prof. Sierra research interest ranges from the study of the behavior of transition metal complexes in their interaction with biomolecules, the mechanisms of transition metal mediated organic and organometallic transformations, with special emphasis in the behavior of densely functionalized organic systems towards organometallic reagents, the synthesis of bio-organometallic compounds, the mechanisms of Fe capture by plants and the design and the synthesis of energetic materials.